                         
<110>  CADILA HEALTHCARE LIMITED
 
<120>  CYCLIC SHORT CHAIN PEPTIDES

<130>  301-MUM-11

<150>  IN:301/MUM/2011
<151>  2011-02-02

<160>  260   

<170>  PatentIn version 3.5

<210>  1
<211>  34
<212>  PRT
<213>  Homo sapiens


<220>
<221>  MISC_FEATURE
<222>  (1)..(34)
<223>  PTH (1-34) is primary structure/sequence alignment of Parathyroid
       Hormone

<400>  1

Ser Val Ser Glu Ile Gln Leu Met His Asn Leu Gly Lys His Leu Asn 
1               5                   10                  15      


Ser Met Glu Arg Val Glu Trp Leu Arg Lys Lys Leu Gln Asp Val His 
            20                  25                  30          


Asn Phe 
        


<210>  2
<211>  14
<212>  PRT
<213>  Homo sapiens


<220>
<221>  MISC_FEATURE
<222>  (1)..(14)
<223>  1-14 N-terminal residues of PTH peptide

<400>  2

Ser Val Ser Glu Ile Gln Leu Met His Asn Leu Gly Lys His 
1               5                   10                  


<210>  3
<211>  15
<212>  PRT
<213>  Homo sapiens


<220>
<221>  MISC_FEATURE
<222>  (1)..(15)
<223>  1-15 N-terminal residues of PTH peptide

<400>  3

Ser Val Ser Glu Ile Gln Leu Met His Asn Leu Gly Lys His Leu 
1               5                   10                  15  


<210>  4
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid (Aib)
       which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid (Aib)
       which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is  alpha-methylphenylalanine 
       (alpha-Me-Phe) which structurally mimics  Phenylalanine

<400>  4

Ala Val Ala Glu Ile Ser Leu Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  5
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is  alpha-methylphenylalanine 
       (alpha-Me-Phe) which structurally mimics  Phenylalanine

<400>  5

Ala Val Ala Glu Ile Ser Leu Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  6
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is  alpha-methylphenylalanine 
       (alpha-Me-Phe) which structurally mimics  Phenylalanine

<400>  6

Ala Val Ala Glu Ile Ser Leu Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  7
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is  alpha-methylphenylalanine 
       (alpha-Me-Phe) which structurally mimics  Phenylalanine

<400>  7

Ala Val Ala Glu Ile Ser Leu Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  8
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is  alpha-methylphenylalanine 
       (alpha-Me-Phe) which structurally mimics  Phenylalanine

<400>  8

Ala Val Ala Glu Ile Ser Leu Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  9
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is  alpha-methylphenylalanine 
       (alpha-Me-Phe) which structurally mimics  Phenylalanine

<400>  9

Ala Val Ala Glu Ile Ser Leu Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  10
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is  alpha-methylphenylalanine 
       (alpha-Me-Phe) which structurally mimics  Phenylalanine

<400>  10

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  11
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is  alpha-methylphenylalanine 
       (alpha-Me-Phe) which structurally mimics  Phenylalanine

<400>  11

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  12
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is  alpha-methylphenylalanine 
       (alpha-Me-Phe) which structurally mimics  Phenylalanine

<400>  12

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  13
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is  alpha-methylphenylalanine 
       (alpha-Me-Phe) which structurally mimics  Phenylalanine

<400>  13

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  14
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is  alpha-methylphenylalanine 
       (alpha-Me-Phe) which structurally mimics  Phenylalanine

<400>  14

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  15
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is  alpha-methylphenylalanine 
       (alpha-Me-Phe) which structurally mimics  Phenylalanine

<400>  15

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  16
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  16

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  17
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  17

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  18
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  18

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  19
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  19

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  20
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  20

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  21
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  21

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  22
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  22

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  23
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  23

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  24
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  24

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  25
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  25

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  26
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  26

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  27
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  27

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  28
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  28

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  29
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  29

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  30
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  30

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  31
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  31

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  32
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  32

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  33
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  33

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  34
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  34

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  35
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  35

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  36
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  36

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  37
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  37

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  38
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  38

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  39
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  39

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  40
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  40

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  41
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  41

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  42
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  42

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  43
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  43

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  44
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  44

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  45
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  45

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  46
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  46

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  47
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  47

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  48
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  48

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  49
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  49

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  50
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  50

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  51
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  51

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  52
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  52

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  53
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  53

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  54
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  54

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  55
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  55

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  56
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  56

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  57
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  57

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  58
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  58

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  59
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  59

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  60
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  60

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  61
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  61

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  62
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  62

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  63
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  63

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Ala Phe 
1               5                   10                  


<210>  64
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  64

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  65
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  65

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  66
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  66

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  67
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  67

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  68
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  68

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  69
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  69

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  70
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  70

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  71
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  71

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  72
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  72

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  73
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  73

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  74
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  74

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  75
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  75

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  76
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  76

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  77
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  77

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  78
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  78

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  79
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  79

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  80
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  80

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  81
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  81

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  82
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  82

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  83
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  83

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  84
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  84

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  85
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  85

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  86
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  86

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  87
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  87

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  88
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  88

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  89
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  89

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  90
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  90

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  91
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  91

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  92
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  92

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  93
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  93

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  94
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  94

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  95
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  95

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  96
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  96

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  97
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  97

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  98
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  98

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  99
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  99

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  100
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  100

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  101
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  101

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  102
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  102

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  103
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  103

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  104
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  104

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  105
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  105

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  106
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  106

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  107
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  107

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  108
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  108

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  109
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  109

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  110
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  110

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  111
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  111

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  112
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Amino acid residue at this position is D-Tryosine (dY)

<400>  112

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  113
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  113

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  114
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  114

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  115
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  115

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  116
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  116

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  117
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  117

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  118
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  118

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  119
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  119

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  120
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  120

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  121
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  121

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  122
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  122

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  123
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  123

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  124
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  124

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  125
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  125

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  126
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  126

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  127
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  127

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  128
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  128

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  129
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  129

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  130
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  130

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  131
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  131

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  132
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  132

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  133
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  133

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  134
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  134

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  135
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Amino acid residue at this position is D-Lysine (dK)

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  135

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  136
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Amino acid residue at this position is D-Lysine (dK)

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  136

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  137
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Amino acid residue at this position is D-Lysine (dK)

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  137

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  138
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Amino acid residue at this position is D-Lysine (dK)

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  138

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  139
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Amino acid residue at this position is D-Lysine (dK)

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  139

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  140
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Amino acid residue at this position is D-Lysine (dK)

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  140

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Lys Phe 
1               5                   10                  


<210>  141
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tryptophan 
       (alpha-Me-Trp) which structurally mimics  tryptophan

<400>  141

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  142
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tryptophan 
       (alpha-Me-Trp) which structurally mimics  tryptophan

<400>  142

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  143
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tryptophan 
       (alpha-Me-Trp) which structurally mimics  tryptophan

<400>  143

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  144
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tryptophan 
       (alpha-Me-Trp) which structurally mimics  tryptophan

<400>  144

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  145
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tryptophan 
       (alpha-Me-Trp) which structurally mimics  tryptophan

<400>  145

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  146
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tryptophan 
       (alpha-Me-Trp) which structurally mimics  tryptophan

<400>  146

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  147
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tryptophan 
       (alpha-Me-Trp) which structurally mimics  tryptophan

<400>  147

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  148
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tryptophan 
       (alpha-Me-Trp) which structurally mimics  tryptophan

<400>  148

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp 
1               5                   10                  


<210>  149
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tyrosine 
       (alpha-Me-Tyr) which structurally mimics  tyrosine

<400>  149

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  150
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tyrosine 
       (alpha-Me-Tyr) which structurally mimics  tyrosine

<400>  150

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  151
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tyrosine 
       (alpha-Me-Tyr) which structurally mimics  tyrosine

<400>  151

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  152
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tyrosine 
       (alpha-Me-Tyr) which structurally mimics  tyrosine

<400>  152

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  153
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tyrosine 
       (alpha-Me-Tyr) which structurally mimics  tyrosine

<400>  153

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  154
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tyrosine 
       (alpha-Me-Tyr) which structurally mimics  tyrosine

<400>  154

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  155
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tyrosine 
       (alpha-Me-Tyr) which structurally mimics  tyrosine

<400>  155

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  156
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tyrosine 
       (alpha-Me-Tyr) which structurally mimics  tyrosine

<400>  156

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Tyr 
1               5                   10                  


<210>  157
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  157

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  158
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  158

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  159
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  159

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  160
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  160

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  161
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  161

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  162
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  162

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  163
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  163

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  164
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  164

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  165
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  165

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  166
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  166

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  167
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  167

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  168
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  168

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  169
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  169

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  170
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  170

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  171
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  171

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  172
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  172

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  173
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  173

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  174
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(6)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (10)..(10)
<223>  Modified residue at this position is Homoserine (HoSer) which 
       structurally mimics  Serine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       alpha-methyl-2,6-F-phenylalanine (alpha-Me-2,6-F-Phe) which 
       structurally mimics  Phenylalanine

<400>  174

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe 
1               5                   10                  


<210>  175
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methylated  
       2'-ethyl-4'-methoxy-biphenylalanine (alpha-methylated Bip(OMe)) 
       which structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  175

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  176
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methylated  
       2'-ethyl-4'-methoxy-biphenylalanine (alpha-methylated Bip(OMe)) 
       which structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  176

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  177
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       2'-ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 
       alpha-methylated-2-Amino-5-phenylpentanoic acid (alpha-Me-APPA) 
       which structurally mimics  Phenylalanine

<400>  177

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  178
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is 
       2'-ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 
       alpha-methylated-2-Amino-5-phenylpentanoic acid (alpha-Me-APPA) 
       which structurally mimics  Phenylalanine

<400>  178

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Phe Phe 
1               5                   10                  15  


<210>  179
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tryptophan 
       (alpha-Me-Trp) which  structurally mimic  tryptophan

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  179

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp Phe 
1               5                   10                  15  


<210>  180
<211>  15
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is alpha-methyl tryptophan 
       (alpha-Me-Trp) which  structurally mimic  tryptophan

<220>
<221>  MISC_FEATURE
<222>  (15)..(15)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics  Phenylalanine

<400>  180

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg Trp Phe 
1               5                   10                  15  


<210>  181
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  181

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg 
1               5                   10              


<210>  182
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  182

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg 
1               5                   10              


<210>  183
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  183

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg 
1               5                   10              


<210>  184
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  184

Ala Val Ala Glu Ile Ser Phe Met His Ser Arg Ala Arg 
1               5                   10              


<210>  185
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  185

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  186
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  186

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  187
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  187

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  188
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  188

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  189
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  189

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  190
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  190

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  191
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  191

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  192
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  192

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  193
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  193

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  194
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  194

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  195
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  195

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  196
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  196

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  197
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  197

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  198
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  198

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  199
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  199

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  200
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  200

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  201
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  201

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  202
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  202

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  203
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  203

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  204
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  204

Ala Val Ala Glu Ile Lys Phe Met Glu Arg Ala Arg Phe 
1               5                   10              


<210>  205
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  205

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  206
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  206

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  207
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  207

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  208
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  208

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  209
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  209

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  210
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  210

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  211
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  211

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  212
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  212

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  213
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  213

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  214
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  214

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  215
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  215

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  216
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  216

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  217
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  217

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  218
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  218

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  219
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  219

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  220
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  220

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  221
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  221

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  222
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  222

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  223
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  223

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  224
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  224

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  225
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  225

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  226
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  226

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  227
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  227

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  228
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  228

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  229
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  229

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  230
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  230

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  231
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  231

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  232
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  232

Ala Val Ala Glu Ile Lys Leu Met His Glu Arg Ala Arg Phe 
1               5                   10                  


<210>  233
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  233

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  234
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  234

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  235
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  235

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  236
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  236

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  237
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  237

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  238
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  238

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  239
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  239

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  240
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  240

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  241
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  241

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  242
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  242

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  243
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  243

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  244
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  244

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  245
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  245

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  246
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  246

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  247
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  247

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  248
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  248

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  249
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  249

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  250
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Citrulline (Cit) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  250

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  251
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  251

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  252
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  252

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  253
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  253

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  254
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  254

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  255
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  255

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  256
<211>  14
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (14)..(14)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<400>  256

Ala Val Ala Glu Ile Lys Leu Met His Asp Arg Ala Arg Phe 
1               5                   10                  


<210>  257
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  257

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg 
1               5                   10              


<210>  258
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  258

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg 
1               5                   10              


<210>  259
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  259

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg 
1               5                   10              


<210>  260
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This cyclic peptide was synthetically generated and prepared


<220>
<221>  MISC_FEATURE
<222>  (1)..(1)
<223>  Modified residue at this position is Amino cyclopentane 
       carboxylic acid (AC5C) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (3)..(3)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (6)..(10)
<223>  When side chains of residues 6 and 10 have acidic/basic groups 
       they form lactam bridge and if side chains of residues 6 and 10 
       have alcohol groups they get cross-linked as a diester bridge

<220>
<221>  MISC_FEATURE
<222>  (7)..(7)
<223>  Modified residue at this position is a 
       alpha-methyl-2F-phenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics  Phenylalanine

<220>
<221>  MISC_FEATURE
<222>  (8)..(8)
<223>  Modified residue at this position is Norleucine (Nle) which 
       structurally mimics  Methionine

<220>
<221>  MISC_FEATURE
<222>  (11)..(11)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<220>
<221>  MISC_FEATURE
<222>  (12)..(12)
<223>  Modified residue at this position is alpha-amino isobutyric acid 
       (Aib) which structurally mimics  Alanine

<220>
<221>  MISC_FEATURE
<222>  (13)..(13)
<223>  Modified residue at this position is Homoarginine (Har) which 
       structurally mimics  Arginine

<400>  260

Ala Val Ala Glu Ile Lys Phe Met His Glu Arg Ala Arg 
1               5                   10              


